Name: Human HepG2 Hepatocellular Carcinoma Cells
SKU: CR1015-500
Price: 325.00 USD
Availability: InStock

Product Overview

HepG2 is a human cell line isolated from a hepatocellular carcinoma of 14 year old male donor. HepG2 cells are used in a wide range of studies, from the oncogenesis to the cytoxicity of substances on the liver

These cells can be used for (i) the study of carcinogenesis as a surrogate for liver toxicity, (ii) the analysis of signaling events, (iii) molecular biology and (iv) protein-based assays. These immortalized hepatic cell lines can be used in place of biopsies for research purposes.

These HepG2 cells are homogenous and grow robustly in cell culture. Vial contains approximately 500,000 cells. Shipped with dry ice.

Cell Characteristics

Description	Data
Growth Properties	Adherent
Donor Age	14 years old
Ethnicity	Caucasian
Gender	Male
Karyotype	Modal number = 55 (range = 50 to 60); has a rearranged chromosome 1
Tumorigenic	No; No, in immunosuppressed mice Yes, in semisolid medium
Genes expressed	alpha-fetoprotein (AFP, alpha-fetoprotein); albumin; alpha2 macroglobulin (alpha-2-macroglobulin); alpha1 antitrypsin (alpha-1-antitrypsin); transferrin; alpha1 antichymotrypsin (alpha-1-antichymotrypsin); haptoglobin; ceruloplasmin; plasminogen, complement (C4); C3 activator; fibrinogen; alpha1 acid glycoprotein (alpha-1 acid glycoprotein); alpha2 HS glycoprotein (alpha-2-HS-glycoprotein); beta lipoprotein (beta-lipoprotein); retinol binding protein (retinol-binding protein)
Expression markers	Insulin: insulin-like growth factor II (IGF II)

Stability & Storage

	Temperature	Storage Time
Human HepG2 Hepatocellular Cells	-80°C (preferably in the vapor phase of a liquid nitrogen storage unit)	12 months
Human HepG2 Hepatocellular Carcinoma Expansion Media (not included)	4°C	3 months
Complete Media (see Media Formulation Instructions)	2-8°C	Not applicable