DISCOVER THE FUNCTIONALITY OF NEXT-GENERATION STEM CELLS
APPLICATIONS
Taking a holistic approach to personalized and regenerative medicine
These are not your grandfather's stem cells.
Leveraging the latest advancements in gene editing, synthetic biology, and cell surface receptor engineering, our proprietary stem cells can be used for various research and therapeutic discovery applications. Discover how iPS cell reprogramming methods have changed, advancing the field since first-generation stem cells.
Hypoimmune Cell Lines
Our immunotolerant stem cells do not express canonical human leukocyte antigen (HLA) molecules, such as major histocompatibility complex (MHC) Class I and Class II. Our proprietary gene-editing methods create cells that obviate the need for HLA-matched haplobanking for allogeneic applications and cell replacement applications. Our starting cell lines leverage our proprietary virus and oncogene-free programming methods to eliminate downstream safety risks and potential off-target effects.
Contact us to discuss how our immunotolerant cells can accelerate your allogeneic research efforts and therapeutic development.
Cell Therapy Development
Induced pluripotent stem cells can be used to reverse injury or disease pathologies by replacing injured or impaired cells and delivering drug payloads. Our iPSCs are programmed using our proprietary method to create the safest starting point for a future therapeutic cell line. We have developed an efficient and scalable episomal DNA vector-based method that provides for virus and oncogene-free cell reprogramming resulting in the safest clinical starting point with the lowest chance of insertional mutagenesis. These cell lines can support adherent and suspension cell culture applications.
Contact our iPSC scientists today to discuss your working cell line development needs.
Disease Modeling
Disease-model iPSCs are a powerful tool in disease modeling for research and pre-IND activities. Our proprietary methods produce differentiated disease-specific induced pluripotent stem cell lines, saving you time and money.
CET's disease-specific iPSC lines allow you to concentrate on your scientific programs and pre-IND activities instead of maintaining vivariums.
OPTIMIZE YOUR CELL-BASED WORKFLOWS
When faced with our own in-house technical challenges and budget constraints, we went back to first principles to design optimized cellular engineering technologies that are scalable, efficient, and cost-effective.
Need a custom solution for a challenging application?
Contact us today to learn how our innovative technological platforms and products can help solve your cell engineering needs.
Drug Development and Discovery
Induced pluripotent stem cells can be used in drug discovery and development by providing human, physiologically relevant cells for compound identification, target validation, compound screening, and biomarker discovery.
Regenerative Medicine
Using iPS cells combined with advanced gene editing, synthetic biology and small molecule engineering has opened new dimensions in personalized therapeutic development and tissue engineering.
Our stem cells can be used for the following applications:
- Organoid and tissue culturing for transplantation research
- Expanding patient stem cell populations for (re)delivery back to the patient
- Synthesizing a custom protein or small molecule that activates specific biological pathways.
Toxicology Studies
The use of induced pluripotent stem cells (iPSC) or tissue-specific cells differentiated from iPS cells in toxicology screening greatly enhances drug discovery and development by providing simple, reproducible, and cost-effective solutions for drug safety testing on living cells.
Contact us today to learn how our innovative technological platforms and products can help solve your cell engineering needs.
OPTIMIZE YOUR CELL-BASED WORKFLOWS
When faced with our own in-house technical challenges and budget constraints, we went back to first principles to design optimized cellular engineering technologies that are scalable, efficient, and cost-effective. Need a custom solution for a challenging application?
Contact us today to learn how our innovative technological platforms and products can help solve your cell engineering needs.